Cargo regulates clathrin-coated pit invagination via clathrin light chain phosphorylation

Clathrin light chains (CLCs) control selective uptake of a range of G protein–coupled receptors (GPCRs), although the mechanism by which this occurs has remained elusive thus far. In particular, site-specific phosphorylation of CLCb controls the uptake of the purinergic GPCR P2Y(12), but it is dispe...

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Publicat a:J Cell Biol
Autors principals: Maib, Hannes, Ferreira, Filipe, Vassilopoulos, Stéphane, Smythe, Elizabeth
Format: Artigo
Idioma:Inglês
Publicat: Rockefeller University Press 2018
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279376/
https://ncbi.nlm.nih.gov/pubmed/30228161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201805005
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