CNS bioavailability and radiation protection of normal hippocampal neurogenesis by a lipophilic Mn porphyrin-based superoxide dismutase mimic, MnTnBuOE-2-PyP(5+)

Although radiation therapy can be effective against cancer, potential damage to normal tissues limits the amount that can be safely administered. In central nervous system (CNS), radiation damage to normal tissues is presented, in part, as suppressed hippocampal neurogenesis and impaired cognitive f...

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Publicat a:Redox Biol
Autors principals: Leu, David, Spasojevic, Ivan, Nguyen, Huy, Deng, Brian, Tovmasyan, Artak, Weitner, Tin, Sampaio, Romulo S., Batinic-Haberle, Ines, Huang, Ting-Ting
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407575/
https://ncbi.nlm.nih.gov/pubmed/28454069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.04.027
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