CNS bioavailability and radiation protection of normal hippocampal neurogenesis by a lipophilic Mn porphyrin-based superoxide dismutase mimic, MnTnBuOE-2-PyP(5+)

Although radiation therapy can be effective against cancer, potential damage to normal tissues limits the amount that can be safely administered. In central nervous system (CNS), radiation damage to normal tissues is presented, in part, as suppressed hippocampal neurogenesis and impaired cognitive f...

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Enregistré dans:
Détails bibliographiques
Publié dans:Redox Biol
Auteurs principaux: Leu, David, Spasojevic, Ivan, Nguyen, Huy, Deng, Brian, Tovmasyan, Artak, Weitner, Tin, Sampaio, Romulo S., Batinic-Haberle, Ines, Huang, Ting-Ting
Format: Artigo
Langue:Inglês
Publié: Elsevier 2017
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407575/
https://ncbi.nlm.nih.gov/pubmed/28454069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.04.027
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