CNS bioavailability and radiation protection of normal hippocampal neurogenesis by a lipophilic Mn porphyrin-based superoxide dismutase mimic, MnTnBuOE-2-PyP(5+)

Although radiation therapy can be effective against cancer, potential damage to normal tissues limits the amount that can be safely administered. In central nervous system (CNS), radiation damage to normal tissues is presented, in part, as suppressed hippocampal neurogenesis and impaired cognitive f...

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Dettagli Bibliografici
Pubblicato in:Redox Biol
Autori principali: Leu, David, Spasojevic, Ivan, Nguyen, Huy, Deng, Brian, Tovmasyan, Artak, Weitner, Tin, Sampaio, Romulo S., Batinic-Haberle, Ines, Huang, Ting-Ting
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407575/
https://ncbi.nlm.nih.gov/pubmed/28454069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.04.027
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