Peroxisome proliferator-activated receptor-α expression induces alterations in cardiac myofilaments in a pressure-overload model of hypertrophy

Although alterations in fatty acid (FA) metabolism have been shown to have a negative impact on contractility of the hypertrophied heart, the targets of action remain elusive. In this study we compared the function of skinned fiber bundles from transgenic (Tg) mice that overexpress a relatively low...

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Bibliografiska uppgifter
I publikationen:Am J Physiol Heart Circ Physiol
Huvudupphovsmän: Karam, Chehade N., Warren, Chad M., Henze, Marcus, Banke, Natasha H., Lewandowski, E. Douglas, Solaro, R. John
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2017
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407160/
https://ncbi.nlm.nih.gov/pubmed/28130336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00469.2016
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