Peroxisome proliferator-activated receptor-α expression induces alterations in cardiac myofilaments in a pressure-overload model of hypertrophy

Although alterations in fatty acid (FA) metabolism have been shown to have a negative impact on contractility of the hypertrophied heart, the targets of action remain elusive. In this study we compared the function of skinned fiber bundles from transgenic (Tg) mice that overexpress a relatively low...

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Foilsithe in:Am J Physiol Heart Circ Physiol
Main Authors: Karam, Chehade N., Warren, Chad M., Henze, Marcus, Banke, Natasha H., Lewandowski, E. Douglas, Solaro, R. John
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Physiological Society 2017
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407160/
https://ncbi.nlm.nih.gov/pubmed/28130336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00469.2016
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