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Chronic anemic hypoxemia attenuates glucose-stimulated insulin secretion in fetal sheep

Fetal insulin secretion is inhibited by acute hypoxemia. The relationship between prolonged hypoxemia and insulin secretion, however, is less well defined. To test the hypothesis that prolonged fetal hypoxemia impairs insulin secretion, studies were performed in sheep fetuses that were bled to anemi...

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Pubblicato in:Am J Physiol Regul Integr Comp Physiol
Autori principali: Benjamin, Joshua S., Culpepper, Christine B., Brown, Laura D., Wesolowski, Stephanie R., Jonker, Sonnet S., Davis, Melissa A., Limesand, Sean W., Wilkening, Randall B., Hay, William W., Rozance, Paul J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407078/
https://ncbi.nlm.nih.gov/pubmed/28100476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00484.2016
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