Chronically Increased Amino Acids Improve Insulin Secretion, Pancreatic Vascularity, and Islet Size in Growth-Restricted Fetal Sheep

Placental insufficiency is associated with reduced supply of amino acids to the fetus and leads to intrauterine growth restriction (IUGR). IUGR fetuses are characterized by lower glucose-stimulated insulin secretion, smaller pancreatic islets with less β-cells, and impaired pancreatic vascularity. T...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Brown, Laura D., Davis, Melissa, Wai, Sandra, Wesolowski, Stephanie R., Hay, William W., Limesand, Sean W., Rozance, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045508/
https://ncbi.nlm.nih.gov/pubmed/27501184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2016-1328
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