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Chronic anemic hypoxemia increases plasma glucagon and hepatic PCK1 mRNA in late-gestation fetal sheep

Hepatic glucose production (HGP) normally begins just prior to birth. Prolonged fetal hypoglycemia, intrauterine growth restriction, and acute hypoxemia produce an early activation of fetal HGP. To test the hypothesis that prolonged hypoxemia increases factors which regulate HGP, studies were perfor...

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Detalhes bibliográficos
Publicado no:Am J Physiol Regul Integr Comp Physiol
Main Authors: Culpepper, Christine, Wesolowski, Stephanie R., Benjamin, Joshua, Bruce, Jennifer L., Brown, Laura D., Jonker, Sonnet S., Wilkening, Randall B., Hay, William W., Rozance, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967231/
https://ncbi.nlm.nih.gov/pubmed/27170658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00037.2016
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