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Chronic anemic hypoxemia increases plasma glucagon and hepatic PCK1 mRNA in late-gestation fetal sheep

Hepatic glucose production (HGP) normally begins just prior to birth. Prolonged fetal hypoglycemia, intrauterine growth restriction, and acute hypoxemia produce an early activation of fetal HGP. To test the hypothesis that prolonged hypoxemia increases factors which regulate HGP, studies were perfor...

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Pubblicato in:Am J Physiol Regul Integr Comp Physiol
Autori principali: Culpepper, Christine, Wesolowski, Stephanie R., Benjamin, Joshua, Bruce, Jennifer L., Brown, Laura D., Jonker, Sonnet S., Wilkening, Randall B., Hay, William W., Rozance, Paul J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967231/
https://ncbi.nlm.nih.gov/pubmed/27170658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00037.2016
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