Functional Analysis of the rs774872314, rs116171003, rs200231898 and rs201107751 Polymorphisms in the Human RORγT Gene Promoter Region

RAR-related orphan receptor gamma RORγT, a tissue-specific isoform of the RORC gene, plays a critical role in the development of naive CD4+ cells into fully differentiated Th17 lymphocytes. Th17 lymphocytes are part of the host defense against numerous pathogens and are also involved in the pathogen...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Ratajewski, Marcin, Słomka, Marcin, Karaś, Kaja, Sobalska-Kwapis, Marta, Korycka-Machała, Małgorzata, Sałkowska, Anna, Dziadek, Jarosław, Strapagiel, Dominik, Dastych, Jarosław
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5406873/
https://ncbi.nlm.nih.gov/pubmed/28430123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes8040126
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