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Genetic variation of the ABC transporter gene ABCC1 (Multidrug resistance protein 1 – MRP1) in the Polish population

BACKGROUND: Multidrug resistance-associated protein 1 (MRP1), encoded by the ABCC1 gene, is an ATP-binding cassette transporter mediating efflux of organic anions and xenobiotics; its overexpression leads to multidrug resistance. In this study, 30 exons (from 31 in total) of the ABCC1 gene as well a...

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Detalhes bibliográficos
Publicado no:BMC Genet
Main Authors: Słomka, Marcin, Sobalska-Kwapis, Marta, Korycka-Machała, Małgorzata, Bartosz, Grzegorz, Dziadek, Jarosław, Strapagiel, Dominik
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4579605/
https://ncbi.nlm.nih.gov/pubmed/26395522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-015-0271-3
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