Proteomic Profiling Reveals a Specific Role for Translesion DNA Polymerase η in the Alternative Lengthening of Telomeres

Cancer cells rely on the activation of telomerase or the alternative lengthening of telomeres (ALT) pathways for telomere maintenance and survival. ALT involves homologous recombination (HR)-dependent exchange and/or HR-associated synthesis of telomeric DNA. Utilizing proximity-dependent biotinylati...

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Bibliografske podrobnosti
izdano v:Cell Rep
Main Authors: Garcia-Exposito, Laura, Bournique, Elodie, Bergoglio, Valérie, Bose, Arindam, Barroso-Gonzalez, Jonathan, Zhang, Sufang, Roncaioli, Justin L., Lee, Marietta, Wallace, Callen T., Watkins, Simon C., Opresko, Patricia L., Hoffmann, Jean-Sébastien, O’Sullivan, Roderick J.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5406014/
https://ncbi.nlm.nih.gov/pubmed/27829156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.10.048
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