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Alternative Lengthening of Telomeres: building bridges to connect chromosome ends

Alternative Lengthening of Telomeres (ALT) is a mechanism of telomere maintenance observed in many of the most recalcitrant cancer subtypes. Telomeres in ALT cancer cells exhibit a distinctive nucleoprotein architecture shaped by the mismanagement of chromatin that fosters cycles of DNA damage and r...

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Publicat a:Trends Cancer
Autors principals: Hoang, Song My, O’Sullivan, Roderick J
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199893/
https://ncbi.nlm.nih.gov/pubmed/32101727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2019.12.009
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