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PARP inhibitors in ovarian cancer: evidence, experience and clinical potential

Inhibitors of poly(ADP-ribose) polymerase (PARP) are considered one of the most active and exciting new therapies for the treatment of ovarian cancer. The anticancer activity of PARP inhibitors is based on the DNA repair vulnerability of many ovarian cancer cells, and multiple mechanisms of action o...

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Detalhes bibliográficos
Publicado no:Ther Adv Med Oncol
Main Authors: Evans, Tarra, Matulonis, Ursula
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405993/
https://ncbi.nlm.nih.gov/pubmed/28491146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758834016687254
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