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PARP inhibitors in ovarian cancer: evidence, experience and clinical potential

Inhibitors of poly(ADP-ribose) polymerase (PARP) are considered one of the most active and exciting new therapies for the treatment of ovarian cancer. The anticancer activity of PARP inhibitors is based on the DNA repair vulnerability of many ovarian cancer cells, and multiple mechanisms of action o...

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Bibliographic Details
Published in:Ther Adv Med Oncol
Main Authors: Evans, Tarra, Matulonis, Ursula
Format: Artigo
Language:Inglês
Published: SAGE Publications 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405993/
https://ncbi.nlm.nih.gov/pubmed/28491146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758834016687254
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