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PARP inhibitors in ovarian cancer: evidence, experience and clinical potential

Inhibitors of poly(ADP-ribose) polymerase (PARP) are considered one of the most active and exciting new therapies for the treatment of ovarian cancer. The anticancer activity of PARP inhibitors is based on the DNA repair vulnerability of many ovarian cancer cells, and multiple mechanisms of action o...

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Dades bibliogràfiques
Publicat a:Ther Adv Med Oncol
Autors principals: Evans, Tarra, Matulonis, Ursula
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405993/
https://ncbi.nlm.nih.gov/pubmed/28491146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758834016687254
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