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Current status and future prospects of PARP inhibitor clinical trials in ovarian cancer
Poly (ADP-ribose) polymerase (PARP) inhibitors are a class of targeted agents for the treatment of solid tumors. Concurrent PARP inhibition in Breast Cancer Susceptibility Gene (BRCA)-mutated or homologous recombination-deficient tumor cells can induce “synthetic lethality”, which targets two DNA re...
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| 出版年: | Cancer Manag Res |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Dove
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6519338/ https://ncbi.nlm.nih.gov/pubmed/31191001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S200524 |
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