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Anti-phospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: beta 2-glycoprotein I (apolipoprotein H).

Anti-phospholipid (aPL) antibodies that exhibit binding in cardiolipin (CL) ELISA can be purified to greater than 95% purity by sequential phospholipid affinity and ion-exchange chromatography. However, these highly purified aPL antibodies do not bind to the CL antigen when assayed by a modified CL...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Proc Natl Acad Sci U S A
Principais autores: McNeil, H P, Simpson, R J, Chesterman, C N, Krilis, S A
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 1990
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54059/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2349221/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.11.4120
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