Engineering cardiolipin binding to an artificial membrane protein reveals determinants for lipid-mediated stabilization

Integral membrane proteins carry out essential functions in the cell, and their activities are often modulated by specific protein-lipid interactions in the membrane. Here, we elucidate the intricate role of cardiolipin (CDL), a regulatory lipid, as a stabilizer of membrane proteins and their comple...

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Autors principals:	Mia L Abramsson, Robin A Corey, Jan L Skerle, Louise J Persson, Olivia Anden, Abraham O Oluwole, Rebecca J Howard, Erik Lindahl, Carol V Robinson, Kvido Strisovsky, Erik G Marklund, David Drew, Phillip J Stansfeld, Michael Landreh
Format:	Artigo
Idioma:	Inglês
Publicat:	eLife Sciences Publications Ltd 2025-04-01
Col·lecció:	eLife
Matèries:	membrane protein mass spectrometry lipid binding
Accés en línia:	https://elifesciences.org/articles/104237
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