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Localization of cofactor binding sites with monoclonal anti-idiotype antibodies: phenylalanine hydroxylase.

A monoclonal anti-idiotype antibody, NS7, previously shown to mimic the binding of the pterin cofactor of phenylalanine hydroxylase (phenylalanine 4-monooxygenase, EC 1.14.16.1) has been used to localize the cofactor binding site within the phenylalanine hydroxylase catalytic domain to a 27-amino-ac...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Jennings, I G, Kemp, B E, Cotton, R G
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51952/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2062852/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.13.5734
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