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Characterization of a monoclonal anti-idiotype antibody to human anti-factor VIII antibodies.

Approximately 15% of individuals with hemophilia A develop antibodies (inhibitors) to therapeutically infused factor VIII that interfere with F.VIII coagulant activity. By using isoelectric focusing and immunospecific detection of anti-factor VIII antibodies, inhibitor plasma showed varied patterns...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Lubahn, B C, Reisner, H M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54929/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2122456/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.21.8232
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