Structural basis of the specificity of USP18 toward ISG15

Protein modification by ubiquitin and ubiquitin-like modifiers (Ubls) is counteracted by ubiquitin proteases and Ubl proteases, collectively termed DUBs. In contrast to other proteases of the ubiquitin-specific protease (USP) family, USP18 shows no reactivity toward ubiquitin but specifically deconj...

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Udgivet i:Nat Struct Mol Biol
Main Authors: Basters, Anja, Geurink, Paul P, Röcker, Annika, Witting, Katharina F, Tadayon, Roya, Hess, Sandra, Semrau, Marta S, Storici, Paola, Ovaa, Huib, Knobeloch, Klaus-Peter, Fritz, Günter
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group US 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405867/
https://ncbi.nlm.nih.gov/pubmed/28165509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3371
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