Sheet-Like Remodeling of the Transverse Tubular System in Human Heart Failure Impairs Excitation-Contraction Coupling and Functional Recovery by Mechanical Unloading

BACKGROUND: Cardiac recovery in response to mechanical unloading by left ventricular assist devices (LVADs) has been demonstrated in subgroups of chronic heart failure (HF) patients. Hallmarks of HF are depletion and disorganization of the transverse tubular system (t-system) in cardiomyocytes. Here...

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Bibliografiska uppgifter
I publikationen:Circulation
Huvudupphovsmän: Seidel, Thomas, Navankasattusas, Sutip, Ahmad, Azmi, Diakos, Nikolaos A., Xu, Weining David, Tristani-Firouzi, Martin, Bonios, Michael J., Taleb, Iosif, Li, Dean Y., Selzman, Craig H., Drakos, Stavros G., Sachse, Frank B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404964/
https://ncbi.nlm.nih.gov/pubmed/28073805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.116.024470
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