Evidence of Glycolysis Up-Regulation and Pyruvate Mitochondrial Oxidation Mismatch During Mechanical Unloading of the Failing Human Heart: Implications for Cardiac Reloading and Conditioning

This study sought to investigate the effects of mechanical unloading on myocardial energetics and the metabolic perturbation of heart failure (HF) in an effort to identify potential new therapeutic targets that could enhance the unloading-induced cardiac recovery. The authors prospectively examined...

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Detalhes bibliográficos
Publicado no:JACC Basic Transl Sci
Main Authors: Diakos, Nikolaos A., Navankasattusas, Sutip, Abel, E. Dale, Rutter, Jared, McCreath, Lauren, Ferrin, Peter, McKellar, Stephen H., Miller, Dylan V., Park, Song Y., Richardson, Russell S., Deberardinis, Ralph, Cox, James E., Kfoury, Abdallah G., Selzman, Craig H., Stehlik, Josef, Fang, James C., Li, Dean Y., Drakos, Stavros G.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
CLINICAL RESEARCH
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5422992/
https://ncbi.nlm.nih.gov/pubmed/28497127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2016.06.009
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