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The PA Endonuclease Inhibitor RO-7 Protects Mice from Lethal Challenge with Influenza A or B Viruses

Current influenza treatment relies on a single class of antiviral drugs, the neuraminidase inhibitors (NAIs), raising concern over the potential emergence of resistant variants and necessitating the development of novel drugs. In recent years, investigational inhibitors targeting the endonuclease ac...

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Detaylı Bibliyografya
Yayımlandı:Antimicrob Agents Chemother
Asıl Yazarlar: Jones, Jeremy C., Marathe, Bindumadhav M., Vogel, Peter, Gasser, Rodolfo, Najera, Isabel, Govorkova, Elena A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404582/
https://ncbi.nlm.nih.gov/pubmed/28193653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02460-16
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