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The PA Endonuclease Inhibitor RO-7 Protects Mice from Lethal Challenge with Influenza A or B Viruses

Current influenza treatment relies on a single class of antiviral drugs, the neuraminidase inhibitors (NAIs), raising concern over the potential emergence of resistant variants and necessitating the development of novel drugs. In recent years, investigational inhibitors targeting the endonuclease ac...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Jones, Jeremy C., Marathe, Bindumadhav M., Vogel, Peter, Gasser, Rodolfo, Najera, Isabel, Govorkova, Elena A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404582/
https://ncbi.nlm.nih.gov/pubmed/28193653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02460-16
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