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The PA Endonuclease Inhibitor RO-7 Protects Mice from Lethal Challenge with Influenza A or B Viruses

Current influenza treatment relies on a single class of antiviral drugs, the neuraminidase inhibitors (NAIs), raising concern over the potential emergence of resistant variants and necessitating the development of novel drugs. In recent years, investigational inhibitors targeting the endonuclease ac...

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Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Jones, Jeremy C., Marathe, Bindumadhav M., Vogel, Peter, Gasser, Rodolfo, Najera, Isabel, Govorkova, Elena A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404582/
https://ncbi.nlm.nih.gov/pubmed/28193653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02460-16
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