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The PA Endonuclease Inhibitor RO-7 Protects Mice from Lethal Challenge with Influenza A or B Viruses

Current influenza treatment relies on a single class of antiviral drugs, the neuraminidase inhibitors (NAIs), raising concern over the potential emergence of resistant variants and necessitating the development of novel drugs. In recent years, investigational inhibitors targeting the endonuclease ac...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Jones, Jeremy C., Marathe, Bindumadhav M., Vogel, Peter, Gasser, Rodolfo, Najera, Isabel, Govorkova, Elena A.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404582/
https://ncbi.nlm.nih.gov/pubmed/28193653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02460-16
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