Determination of Neuraminidase Kinetic Constants Using Whole Influenza Virus Preparations and Correction for Spectroscopic Interference by a Fluorogenic Substrate

Por Marathe, Bindumadhav M., Lévêque, Vincent, Klumpp, Klaus, Webster, Robert G., Govorkova, Elena A.
Publicado em 2013

Assessment of the efficacy of the neuraminidase inhibitor oseltamivir against 2009 pandemic H1N1 influenza virus in ferrets

Por Govorkova, Elena A., Marathe, Bindumadhav M., Prevost, Ashley, Rehg, Jerold E., Webster, Robert G.
Publicado em 2011

Antiplatelet antibodies in WASP(−) mice correlate with evidence of increased in vivo platelet consumption

Por Marathe, Bindumadhav M., Prislovsky, Amanda, Astrakhan, Alexander, Rawlings, David J, Wan, Jim Y., Strom, Ted S.
Publicado em 2009

Competitive Fitness of Oseltamivir-Sensitive and -Resistant Highly Pathogenic H5N1 Influenza Viruses in a Ferret Model

Por Govorkova, Elena A., Ilyushina, Natalia A., Marathe, Bindumadhav M., McClaren, Jennifer L., Webster, Robert G.
Publicado em 2010

Fitness Costs for Influenza B Viruses Carrying Neuraminidase Inhibitor-Resistant Substitutions: Underscoring the Importance of E119A and H274Y

Por Burnham, Andrew J., Baranovich, Tatiana, Marathe, Bindumadhav M., Armstrong, Jianling, Webster, Robert G., Govorkova, Elena A.
Publicado em 2014

Influenza A Virus-Induced Early Activation of ERK and PI3K Mediates V-ATPase-Dependent Intracellular pH Change Required for Fusion

Por Marjuki, Henju, Gornitzky, Alex, Marathe, Bindumadhav M., Ilyushina, Natalia A., Aldridge, Jerry R., Desai, Gururao, Webby, Richard J., Webster, Robert G.
Publicado em 2010

Sialic Acid-Binding Protein Sp2CBMTD Protects Mice against Lethal Challenge with Emerging Influenza A (H7N9) Virus

Por Govorkova, Elena A., Baranovich, Tatiana, Marathe, Bindumadhav M., Yang, Lei, Taylor, Margaret A., Webster, Robert G., Taylor, Garry L., Connaris, Helen
Publicado no Antimicrob Agents Chemother (2015)

Competitive Fitness of Influenza B Viruses Possessing E119A and H274Y Neuraminidase Inhibitor Resistance–Associated Substitutions in Ferrets

Por Pascua, Philippe Noriel Q., Marathe, Bindumadhav M., Burnham, Andrew J., Vogel, Peter, Webby, Richard J., Webster, Robert G., Govorkova, Elena A.
Publicado no PLoS One (2016)

A Novel Endonuclease Inhibitor Exhibits Broad-Spectrum Anti-Influenza Virus Activity In Vitro

Por Jones, Jeremy C., Marathe, Bindumadhav M., Lerner, Christian, Kreis, Lukas, Gasser, Rodolfo, Pascua, Philippe Noriel Q., Najera, Isabel, Govorkova, Elena A.
Publicado no Antimicrob Agents Chemother (2016)

Combinations of Oseltamivir and T-705 Extend the Treatment Window for Highly Pathogenic Influenza A(H5N1) Virus Infection in Mice

Por Marathe, Bindumadhav M., Wong, Sook-San, Vogel, Peter, Garcia-Alcalde, Fernando, Webster, Robert G., Webby, Richard J., Najera, Isabel, Govorkova, Elena A.
Publicado no Sci Rep (2016)

Does Pandemic A/H1N1 Virus Have the Potential To Become More Pathogenic?

Por Ilyushina, Natalia A., Ducatez, Mariette F., Rehg, Jerold E., Marathe, Bindumadhav M., Marjuki, Henju, Bovin, Nicolai V., Webster, Robert G., Webby, Richard J.
Publicado em 2010

Oseltamivir Population Pharmacokinetics in the Ferret: Model Application for Pharmacokinetic/Pharmacodynamic Study Design

Por Reddy, Micaela B., Yang, Kuo-Hsiung, Rao, Gauri, Rayner, Craig R., Nie, Jing, Pamulapati, Chandrasena, Marathe, Bindumadhav M., Forrest, Alan, Govorkova, Elena A.
Publicado no PLoS One (2015)

Risk Assessment of H2N2 Influenza Viruses from the Avian Reservoir

Por Jones, Jeremy C., Baranovich, Tatiana, Marathe, Bindumadhav M., Danner, Angela F., Seiler, Jon P., Franks, John, Govorkova, Elena A., Krauss, Scott, Webster, Robert G.
Publicado em 2014

Influenza A viruses of swine circulating in the United States during 2009–2014 are susceptible to neuraminidase inhibitors but show lineage-dependent resistance to adamantanes

Por Baranovich, Tatiana, Bahl, Justin, Marathe, Bindumadhav M., Culhane, Marie, Stigger-Rosser, Evelyn, Darnell, Daniel, Kaplan, Bryan S., Lowe, James F., Webby, Richard J., Govorkova, Elena A.
Publicado no Antiviral Res (2015)

The Neuraminidase Inhibitor Oseltamivir Is Effective Against A/Anhui/1/2013 (H7N9) Influenza Virus in a Mouse Model of Acute Respiratory Distress Syndrome

Por Baranovich, Tatiana, Burnham, Andrew J., Marathe, Bindumadhav M., Armstrong, Jianling, Guan, Yi, Shu, Yuelong, Peiris, Joseph Malik Sriyal, Webby, Richard J., Webster, Robert G., Govorkova, Elena A.
Publicado em 2014

Unique Determinants of Neuraminidase Inhibitor Resistance among N3, N7, and N9 Avian Influenza Viruses

Por Song, Min-Suk, Marathe, Bindumadhav M., Kumar, Gyanendra, Wong, Sook-San, Rubrum, Adam, Zanin, Mark, Choi, Young-Ki, Webster, Robert G., Govorkova, Elena A., Webby, Richard J.
Publicado no J Virol (2015)

The replication of Bangladeshi H9N2 avian influenza viruses carrying genes from H7N3 in mammals

Por Shanmuganatham, Karthik K, Jones, Jeremy C, Marathe, Bindumadhav M, Feeroz, Mohammed M, Jones-Engel, Lisa, Walker, David, Turner, Jasmine, Rabiul Alam, S M, Kamrul Hasan, M, Akhtar, Sharmin, Seiler, Patrick, McKenzie, Pamela, Krauss, Scott, Webby, Richard J, Webster, Robert G
Publicado no Emerg Microbes Infect (2016)