Fitness Costs for Influenza B Viruses Carrying Neuraminidase Inhibitor-Resistant Substitutions: Underscoring the Importance of E119A and H274Y

Influenza B viruses cause annual outbreaks of respiratory illness in humans and are increasingly recognized as a major cause of influenza-associated pediatric mortality. Neuraminidase (NA) inhibitors (NAIs) are the only available therapy for patients infected with influenza B viruses, and the potent...

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Détails bibliographiques
Auteurs principaux: Burnham, Andrew J., Baranovich, Tatiana, Marathe, Bindumadhav M., Armstrong, Jianling, Webster, Robert G., Govorkova, Elena A.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2014
Sujets:
Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993273/
https://ncbi.nlm.nih.gov/pubmed/24566185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02628-13
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