Competitive Fitness of Influenza B Viruses with Neuraminidase Inhibitor-Resistant Substitutions in a Coinfection Model of the Human Airway Epithelium

Influenza A and B viruses are human pathogens that are regarded to cause almost equally significant disease burdens. Neuraminidase (NA) inhibitors (NAIs) are the only class of drugs available to treat influenza A and B virus infections, so the development of NAI-resistant viruses with superior fitne...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Burnham, Andrew J., Armstrong, Jianling, Lowen, Anice C., Webster, Robert G., Govorkova, Elena A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442356/
https://ncbi.nlm.nih.gov/pubmed/25673705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02473-14
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