Paritaprevir and Ritonavir Liver Concentrations in Rats as Assessed by Different Liver Sampling Techniques

The liver is crucial to pharmacology, yet substantial knowledge gaps exist in the understanding of its basic pharmacologic processes. An improved understanding for humans requires reliable and reproducible liver sampling methods. We compared liver concentrations of paritaprevir and ritonavir in rats...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Venuto, Charles S., Markatou, Marianthi, Woolwine-Cunningham, Yvonne, Furlage, Rosemary, Ocque, Andrew J., DiFrancesco, Robin, Dumas, Emily O., Wallace, Paul K., Morse, Gene D., Talal, Andrew H.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404580/
https://ncbi.nlm.nih.gov/pubmed/28264852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02283-16
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