Paritaprevir and Ritonavir Liver Concentrations in Rats as Assessed by Different Liver Sampling Techniques

The liver is crucial to pharmacology, yet substantial knowledge gaps exist in the understanding of its basic pharmacologic processes. An improved understanding for humans requires reliable and reproducible liver sampling methods. We compared liver concentrations of paritaprevir and ritonavir in rats...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Venuto, Charles S., Markatou, Marianthi, Woolwine-Cunningham, Yvonne, Furlage, Rosemary, Ocque, Andrew J., DiFrancesco, Robin, Dumas, Emily O., Wallace, Paul K., Morse, Gene D., Talal, Andrew H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404580/
https://ncbi.nlm.nih.gov/pubmed/28264852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02283-16
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