Paritaprevir and Ritonavir Liver Concentrations in Rats as Assessed by Different Liver Sampling Techniques

The liver is crucial to pharmacology, yet substantial knowledge gaps exist in the understanding of its basic pharmacologic processes. An improved understanding for humans requires reliable and reproducible liver sampling methods. We compared liver concentrations of paritaprevir and ritonavir in rats...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Venuto, Charles S., Markatou, Marianthi, Woolwine-Cunningham, Yvonne, Furlage, Rosemary, Ocque, Andrew J., DiFrancesco, Robin, Dumas, Emily O., Wallace, Paul K., Morse, Gene D., Talal, Andrew H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404580/
https://ncbi.nlm.nih.gov/pubmed/28264852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02283-16
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