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Paritaprevir and Ritonavir Liver Concentrations in Rats as Assessed by Different Liver Sampling Techniques

The liver is crucial to pharmacology, yet substantial knowledge gaps exist in the understanding of its basic pharmacologic processes. An improved understanding for humans requires reliable and reproducible liver sampling methods. We compared liver concentrations of paritaprevir and ritonavir in rats...

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發表在:Antimicrob Agents Chemother
Main Authors: Venuto, Charles S., Markatou, Marianthi, Woolwine-Cunningham, Yvonne, Furlage, Rosemary, Ocque, Andrew J., DiFrancesco, Robin, Dumas, Emily O., Wallace, Paul K., Morse, Gene D., Talal, Andrew H.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404580/
https://ncbi.nlm.nih.gov/pubmed/28264852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02283-16
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