Loss of hepatic DEPTOR alters the metabolic transition to fasting

OBJECTIVE: The mechanistic target of rapamycin (mTOR) is a serine/threonine kinase that functions into distinct protein complexes (mTORC1 and mTORC2) that regulates growth and metabolism. DEP-domain containing mTOR-interacting protein (DEPTOR) is part of these complexes and is known to reduce their...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Caron, Alexandre, Mouchiroud, Mathilde, Gautier, Nicolas, Labbé, Sébastien M., Villot, Romain, Turcotte, Laurie, Secco, Blandine, Lamoureux, Guillaume, Shum, Michael, Gélinas, Yves, Marette, André, Richard, Denis, Sabatini, David M., Laplante, Mathieu
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404102/
https://ncbi.nlm.nih.gov/pubmed/28462079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.02.005
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