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PUMA decreases the growth of prostate cancer PC-3 cells independent of p53

PUMA (p53 upregulated modulator of apoptosis), a member of the B-cell lymphoma 2 (Bcl-2) protein family, is a pro-apoptotic protein. PUMA expression is modulated by the tumor suppressor p53. PUMA has a role in rapid cell death via p53-dependent and -independent mechanisms. To evaluate whether p53 is...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Shan, Zhengfei, Liu, Qingzuo, Li, Yuling, Wu, Jitao, Sun, Dekang, Gao, Zhenli
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403223/
https://ncbi.nlm.nih.gov/pubmed/28454339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.5657
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