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Metal Ion Binding at the Catalytic Site Induces Widely Distributed Changes in a Sequence Specific Protein–DNA Complex
[Image: see text] Metal ion cofactors can alter the energetics and specificity of sequence specific protein–DNA interactions, but it is unknown if the underlying effects on structure and dynamics are local or dispersed throughout the protein–DNA complex. This work uses EcoRV endonuclease as a model,...
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| Publicat a: | Biochemistry |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American
Chemical Society
2016
|
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5402698/ https://ncbi.nlm.nih.gov/pubmed/27786446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00919 |
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