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Specific Labeling of Threonine Methyl Groups for NMR Studies of Protein-Nucleic Acid Complexes

Specific (13)C labeling of Thr methyl groups has been accomplished by growth of a standard laboratory strain of Escherichia coli on [2-(13)C] glycerol in the presence of deuterated isoketovalerate, Ile, and Ala. Diversion of label from the Thr biosynthetic pathway is suppressed by including Lys, Met...

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Autori principali: Sinha, Kaustubh, Jen-Jacobson, Linda, Rule, Gordon S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222749/
https://ncbi.nlm.nih.gov/pubmed/22039762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201496d
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