Bidirectional KCNQ1:β-catenin interaction drives colorectal cancer cell differentiation

The K(+) channel KCNQ1 has been proposed as a tumor suppressor in colorectal cancer (CRC). We investigated the molecular mechanisms regulating KCNQ1:β-catenin bidirectional interactions and their effects on CRC differentiation, proliferation, and invasion. Molecular and pharmacologic approaches were...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Rapetti-Mauss, Raphael, Bustos, Viviana, Thomas, Warren, McBryan, Jean, Harvey, Harry, Lajczak, Natalia, Madden, Stephen F., Pellissier, Bernard, Borgese, Franck, Soriani, Olivier, Harvey, Brian J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5402468/
https://ncbi.nlm.nih.gov/pubmed/28373572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1702913114
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados