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Oestrogen promotes KCNQ1 potassium channel endocytosis and postendocytic trafficking in colonic epithelium
The cAMP-regulated potassium channel KCNQ1:KCNE3 plays an essential role in transepithelial Cl(−) secretion. Recycling of K(+) across the basolateral membrane provides the driving force necessary to maintain apical Cl(−) secretion. The steroid hormone oestrogen (17β-oestradiol; E(2)), produces a fem...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3690688/ https://ncbi.nlm.nih.gov/pubmed/23529131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.251678 |
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