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Effects of KCNQ channel modulators on the M-type potassium current in primate retinal pigment epithelium

Recently, we demonstrated the expression of KCNQ1, KCNQ4, and KCNQ5 transcripts in monkey retinal pigment epithelium (RPE) and showed that the M-type current in RPE cells is blocked by the specific KCNQ channel blocker XE991. Using patch-clamp electrophysiology, we investigated the pharmacological s...

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Autori principali: Pattnaik, Bikash R., Hughes, Bret A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311298/
https://ncbi.nlm.nih.gov/pubmed/22135213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00269.2011
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