Regulation of Kir channels in bovine retinal pigment epithelial cells by phosphatidylinositol 4,5-bisphosphate

The inwardly rectifying K(+) (Kir) current in mammalian retinal pigment epithelial (RPE) cells, which is largely mediated by Kir7.1 channels, is stable in cells dialyzed with MgATP but runs down when intracellular ATP is depleted. A potential mechanism for this rundown is a decrease in phosphatidyli...

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Bibliographic Details
Main Authors: Pattnaik, Bikash R., Hughes, Bret A.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2009
Subjects:
Membrane Transporters, Ion Channels, and Pumps
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770741/
https://ncbi.nlm.nih.gov/pubmed/19641096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00250.2009
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