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Oestrogen promotes KCNQ1 potassium channel endocytosis and postendocytic trafficking in colonic epithelium

The cAMP-regulated potassium channel KCNQ1:KCNE3 plays an essential role in transepithelial Cl(−) secretion. Recycling of K(+) across the basolateral membrane provides the driving force necessary to maintain apical Cl(−) secretion. The steroid hormone oestrogen (17β-oestradiol; E(2)), produces a fem...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rapetti-Mauss, Raphael, O'Mahony, Fiona, Sepulveda, Francisco V, Urbach, Valerie, Harvey, Brian J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Blackwell Science Inc 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690688/
https://ncbi.nlm.nih.gov/pubmed/23529131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.251678
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