Sexual dimorphism and oestrogen regulation of KCNE3 expression modulates the functional properties of KCNQ1 K(+) channels

ABSTRACT: The KCNQ1 potassium channel associates with various KCNE ancillary subunits that drastically affect channel gating and pharmacology. Co-assembly with KCNE3 produces a current with nearly instantaneous activation, some time-dependent activation at very positive potentials, a linear current–...

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Detalhes bibliográficos
Main Authors: Alzamora, Rodrigo, O'Mahony, Fiona, Bustos, Viviana, Rapetti-Mauss, Raphael, Urbach, Valérie, Cid, L Pablo, Sepúlveda, Francisco V, Harvey, Brian J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2011
Assuntos:
Molecular and Cellular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225667/
https://ncbi.nlm.nih.gov/pubmed/21911611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.215772
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