NEIL1 protects against aflatoxin-induced hepatocellular carcinoma in mice

Global distribution of hepatocellular carcinomas (HCCs) is dominated by its incidence in developing countries, accounting for >700,000 estimated deaths per year, with dietary exposures to aflatoxin (AFB(1)) and subsequent DNA adduct formation being a significant driver. Genetic variants that incr...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Vartanian, Vladimir, Minko, Irina G., Chawanthayatham, Supawadee, Egner, Patricia A., Lin, Ying-Chih, Earley, Lauriel F., Makar, Rosemary, Eng, Jennifer R., Camp, Matthew T., Li, Liang, Stone, Michael P., Lasarev, Michael R., Groopman, John D., Croy, Robert G., Essigmann, John M., McCullough, Amanda K., Lloyd, R. Stephen
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2017
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5402411/
https://ncbi.nlm.nih.gov/pubmed/28373545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620932114
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