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Rational design of non-resistant targeted cancer therapies

Drug resistance is one of the major problems in targeted cancer therapy. A major cause of resistance is changes in the amino acids that form the drug-target binding site. Despite of the numerous efforts made to individually understand and overcome these mutations, there is a lack of comprehensive an...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Martínez-Jiménez, Francisco, Overington, John P., Al-Lazikani, Bissan, Marti-Renom, Marc A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5402386/
https://ncbi.nlm.nih.gov/pubmed/28436422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46632
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