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Rapid, High-Throughput, Multiplex, Real-Time PCR for Identification of Mutations in the cyp51A Gene of Aspergillus fumigatus That Confer Resistance to Itraconazole

Aspergillus fumigatus is an important cause of life-threatening invasive fungal disease in patients with compromised immune systems. Resistance to itraconazole in A. fumigatus is closely linked to amino acid substitutions in Cyp51A that replace Gly54. In an effort to develop a new class of molecular...

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Detalhes bibliográficos
Main Authors: Balashov, Sergey V., Gardiner, Rebecca, Park, Steven, Perlin, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC540178/
https://ncbi.nlm.nih.gov/pubmed/15634974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.43.1.214-222.2005
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