Genetic Otx2 mis-localization delays critical period plasticity across brain regions

Accumulation of non-cell autonomous Otx2 homeoprotein in postnatal mouse visual cortex (V1) has been implicated in both the onset and closure of critical period plasticity. Here, we show that a genetic point mutation in the glycosaminoglycan-recognition motif of Otx2 broadly delays the maturation of...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Mol Psychiatry
Main Authors: Lee, Henry Hing Cheong, Bernard, Clémence, Ye, Zhanlei, Acampora, Dario, Simeone, Antonio, Prochiantz, Alain, Di Nardo, Ariel A, Hensch, Takao K
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400722/
https://ncbi.nlm.nih.gov/pubmed/28194008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2017.1
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker