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Choroid plexus-derived Otx2 homeoprotein constrains adult cortical plasticity
Brain plasticity is often restricted to critical periods in early life. Here, we show that a key regulator of this process in visual cortex, Otx2 homeoprotein, is synthesized and secreted globally from the choroid plexus. Consequently, Otx2 is maintained in selected GABA cells unexpectedly throughou...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4119931/ https://ncbi.nlm.nih.gov/pubmed/23770240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.05.014 |
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