Otx2 Binding to Perineuronal Nets Persistently Regulates Plasticity in the Mature Visual Cortex

Specific transfer of (orthodenticle homeobox 2) Otx2 homeoprotein into GABAergic interneurons expressing parvalbumin (PV) is necessary and sufficient to open, then close, a critical period (CP) of plasticity in the developing mouse visual cortex. The accumulation of endogenous Otx2 in PV cells sugge...

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Autori principali: Beurdeley, Marine, Spatazza, Julien, Lee, Henry H. C., Sugiyama, Sayaka, Bernard, Clémence, Di Nardo, Ariel A., Hensch, Takao K., Prochiantz, Alain
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419577/
https://ncbi.nlm.nih.gov/pubmed/22764251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0394-12.2012
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